Analytical Unit Manager HPLC

We are seeking for Analytical Unit Manager

The Analytical Manager heads the Analytical Unit, overseeing method development, validation, and routine analysis to support R&D programs. This role has a strong emphasis

on High-Performance Liquid Chromatography (HPLC) for protein and polyphenol analysis,

but also covers other analytical techniques essential for product characterization and quality assessment. The Analytical Manager also acts as a technical representative in

discussions with collaborators, partners, and companies seeking the organization’s analytical services, ensuring scientific excellence and alignment with project needs.

Key Responsibilities

Leadership & Unit Management

-Lead the Analytical Unit, managing daily operations, workload allocation, and staff performance.

- Mentor and train analysts in advanced analytical methods, focusing on HPLC/UPLC for proteins and polyphenols.

- Ensure compliance with internal quality systems, GLP/GMP as needed.

Analytical Method Development & Validation

- Develop, optimize, and validate analytical methods for active compounds, including proteins (e.g., enzymes such as bromelain) and polyphenols (e.g.resveratrol, verbascoside).

-Implement robust sample preparation protocols for diverse biological matrices, including plant cell cultures, extracts, and finished formulations.

-Ensure analytical methods meet project requirements and regulatory guidelines.

External Collaboration & Representation

-Participate in technical discussions with collaborators, partners, and companies requesting analytical services.

-Provide scientific input, explain analytical capabilities, and help define testing scope and timelines for joint projects.

- Represent the Analytical Unit in partnership meetings, ensuring alignment between analytical deliverables and project objectives.

Laboratory Operations

-Oversee instrument maintenance, calibration, and troubleshooting, ensuring minimal downtime.

-Manage laboratory inventory, consumables, and procurement for analytical activities.

-Maintain accurate, complete, and auditable documentation of analytical processes and results.

Data Analysis & Reporting

- Interpret analytical data and provide clear, actionable reports for R&D, QA, and regulatory purposes.

- Review and approve analytical results, ensuring scientific accuracy and data integrity.

- Present analytical findings in project review meetings and technical discussions. Cross-Functional Collaboration

- Work closely with R&D teams to support formulation development, stability studies, and process optimization.

-Provide analytical expertise in troubleshooting and root cause analysis.

Continuous Improvement & Innovation

- Stay informed on new analytical technologies and best practices in chromatography, spectroscopy, and bioanalytical methods.

- Recommend and implement improvements to enhance analytical efficiency and accuracy.

Qualifications & Experience:

- PhD in Analytical Chemistry, Biochemistry, or related scientific discipline.

- 5+ years of experience in analytical method development and validation, with proven HPLC/UPLC expertise.

- Direct experience in protein and polyphenol analysis.

-Knowledge of GMP/GLP, ICH, and regulatory analytical requirements.

- Strong leadership skills

- Excellent organizational, problem-solving, and communication skills.

- Experience in representing technical capabilities in external collaborations or customer meetings is an advantage.

- Verbal and written communication – Hebrew and English – a must

-Full-time position in Rehovot/Yavne