Computational Drug Discovery Scientist / Protein Engineering

Company Overview:

Trojan-bio, a leading biotech innovator based in Yavne, Israel, is dedicated to revolutionizing cancer treatment through the development of cutting-edge bi-functional antibodies. Join our dynamic R&D team and play a pivotal role in shaping the future of immunotherapy.

Position Summary:

We are seeking an experienced antibody/protein engineer to facilitate our R&D efforts. As a key member of our multidisciplinary team, you will drive the discovery, design, and optimization of novel immunotherapy modalities using state-of-the-art computational and structural methods.

Key Responsibilities:

·       Lead the implementation of cutting-edge structural methods, including molecular dynamics simulations, homology modelling, and docking studies, to design breakthrough drug candidates.

·       Harness AI/ML approaches and Antibody/Protein Engineering techniques to discover and optimize therapeutic antibodies.

·       Stay abreast of emerging technologies in structural biology and integrate novel approaches into our research programs to maintain our competitive edge.

·       Collaborate closely with laboratory personnel and Contract Research Organizations (CRO) to oversee antibody expression, quality control, and efficacy testing.

·       Contribute to project planning, scheduling, and cost estimation, ensuring timely and cost-effective delivery of assigned projects.

·       Foster a culture of collaboration and excellence by building effective working relationships with colleagues, management, and external partners.

Qualifications and Experience:

·       PhD in Computational Structural Biology, Bioinformatics, or a related field. (Or Ms.C with extensive relevant industrial record)

·       Minimum of 3 years' experience in designing or optimizing novel proteins or antibodies.

·       Proficiency in molecular modelling, simulation, and visualization packages.

·       Expertise in computational biology, including AI/ML approaches and bioinformatics tools (e.g., AlphaFold, ESM, Rosetta), with experience in Linux and cloud environments and proficiency in Python.

·       Proven ability to manage multiple projects simultaneously in a fast-paced, milestone-driven environment.

·       Strong oral and written communication skills, with experience presenting scientific data to diverse audiences.

Personal Attributes:

·       Collaborative team player with excellent interpersonal skills.

·       Demonstrated creativity and an open mindset toward innovation.

·       Strong analytical and problem-solving abilities, underpinned by integrity in decision-making.

·       Meticulous organizational skills with a focus on record-keeping and reporting.

How to Apply:

To join our dynamic team and contribute to the future of cancer treatment, please submit your CV to [email protected].